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Nutrients 12(9):2499

Preliminary clinical studies have reported that MLT may have beneficial effects on patients with gastrointestinal tumors, either alone or in combination with other therapeutic agents

To regulate mitochondrial ROS levels (e.g., superoxide (O 2 - )), superoxide dismutase 2 (SOD2) converts superoxide to hydrogen peroxide (H 2 O 2 )

To view a copy of this licence, visit About this article Cite this article Malikov, D., Krasnov, L., Kiseleva, M

Moreover, exercise stimulates the release of angiogenic myokines via the muscle-brain axis, including IL-6, irisin, and follistatin-like 1 (FSTL1), upregulating VEGF and membrane-type I matrix metalloproteinase (MT1-MMP) to facilitate endothelial cell migration and lumen formation [281]