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Both mRNA platforms offer the ability to rapidly update their vaccines in response to evolving viral variants, however, Pfizer/BioNTech has been more proactive in targeting specific COVID-19 variants, such as Omicron, in their combination vaccines 41

There are some very rare side effects listed in medical literature (mostly when large doses are given): for example, one out of many thousands of patients might develop a disturbance in liver enzymes or a tingling in the fingers or toes

Therefore, it would have been questionable if a baseline pain score would really picture the baseline severity of pain or rather the efficiency of the already applied analgesic treatment

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Lane K, Dixon JJ, Macphee IAM, Philips BJ (2013) Renohepatic crosstalk: does acute kidney injury cause liver dysfunction