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& Dolores Dor Eccles Professor of Ophthalmology & Neuroscience, Wilmer Eye Institute, The Johns Hopkins School of Medicine involving oxidative stress in the retina provided impetus for exploring small molecule antioxidant therapies

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One important source of LIP expansion is the selective autophagic degradation of ferritin, which leads to the accumulation of iron in the cytoplasm in the form of Fe 2+

Initial improvements can be seen within 46 weeks , with full results in 36 months

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