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Conversely, macrophages similar to M2 enhance tumor blood vessel formation, immune suppression, cancer cell infiltration, and spread by emitting anti-inflammatory agents such as TGF-, PGE2, and VEGF [61]

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Recent studies highlight cases where patients with normal B12 levels received initial MDS diagnoses based on bone marrow biopsies

[DOI] [PubMed] [Google Scholar] 64.Villa I, Melzi R, Pagani F, Ravasi F, Rubinacci A, Guidobono F

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