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The first tesamorelin human trials (Phase 1) began in the early 2000s, with Phase 3 trial dates spanning 2005-2008 (Study LIPO-010 Phase 3 completed 2008), leading to the November 2010 approval

This is receptor adaptation, not a results phase

While a blood test is the definitive way to diagnose a clinical deficiency, it isnt always required to start B12 injections for general wellness purposes

This can lead to Chronic Renal Failure (CRF) or kidney failure, a leading cause of illness in dogs and cats