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European Journal of Medicinal Chemistry 2025 , 300 , 118141

[DOI] [PubMed] [Google Scholar] 40.Frye R.E., Delatorre R., Taylor H., Slattery J., Melnyk S., Chowdhury N., James S.J

This study included 12 week-old Wistar albino male rats that were bred in-house at the animal facility at the Department of Pharmacology, School of Medicine in Zagreb, Croatia

Behavioral assessments revealed that quercetin-treated rats exhibited improved social interaction, exploratory behavior, and cognitive function

Subsequent mechanistic studies were conducted by the Porter and Pryor laboratories using C18:3 substrates, undoubtedly due to the ready availability of these plant-derived fatty acids in the 1970s