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& Lupski, J

Short versus long half-lives Drugs or substances that have a shorter half-life tend to act very quickly, but their effects wear off rapidly, meaning that they usually need to be taken several times a day to have the same effect

J Agric Food Chem 55, 10016 10021
Treatment with more-specific inhibitors, such as triple-helical peptide inhibitors, which target MMP9 and MMP2, reduces EAE severity 133

Subsequently, 10-l VAMP2/Syt1 SUVs (5 nmol lipid) were spun at 20,000 g for 5 min to remove larger SUV complexes and the supernatant was added to the GUV suspension