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In addition, the high costs of the preparation technology used and certain stability problems can create difficulties in the clinical expansion of these types of formulations [219,221]

Sublingual and buccal area is highly perfused with blood vessels

PLoS ONE 7:e53178 Liu Y, Qin X, Lu X (2018) Crocin improves endometriosis by inhibiting cell proliferation and the release of inflammatory factors

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Furthermore, we also show neuroprotection and motor improvement in an in vivo mouse model of neurodegeneration 18
