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As age increases, significant changes occur in the body's metabolic pathways, and serine metabolism, as a key amino acid metabolic pathway, plays a crucial role in the aging process

With the development of science and technology, machine perfusion combined with cryopreservation, CRISPR/Cas 9, stem cell therapy, siRNA, etc, to achieve in vitro editing of donor organs and modify the immunogenicity of donors, which can reduce IRI and immune rejection of the graft, and help the long-term survival of the graft (193197)

All solutions were protected from light during the stability period

Abstract Bloodbrain barrier (BBB) is a natural protective membrane that prevents central nervous system (CNS) from toxins and pathogens in blood

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