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We hypothesize that the lactate-H3K18la epigenetic axis, the TREM2-SHP1-BTK signaling pathway and itaconate-mediated mitochondrial modulation regulatory nodes in sepsis can function as synchronous elements rather than isolated metabolic changes (25,68,189,190)

(7) clinically significant hypersensitivity to collagen components

433 Additionally, MSCs can be engineered to secrete tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and other proapoptotic factors to induce cancer cell death

Concentrations in PBS were 100-fold lower than those used for MIC testing, at 1128 mg/L, whereas those in CAMHB were identical to the ones used in MIC testing, ranging 10012,800 mg/L