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EGCG reduces inflammation-related chemicals and infarct volume and might be a potential treatment for cerebral IRI [84]
Flaxseed lignans, a plant estrogen structurally analogous to human estrogen, enhances the efficacy of PD-1/PD-L1 inhibitor against BC by modulating the gut microbiota and regulating immunity to remodel the TME [243]
This is achieved through mechanisms such as PR- and Nef-dependent induction of regulated upon activation, normal T cell expressed and secreted/C-C chemokine ligand 5 [12, 13]
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