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Shaking adds air, creates foam, and can fracture peptide bonds

While that could be beneficial if youre wanting to incite hair growth, on the flipside, it would be a deterrent if you do not want to stimulate hair growth (such as on the face) while using skin care products that contain copper tripeptide-1
How peptide therapy works: Specific peptides are administered via injections, creams, or pills
120 PacaA

Selectively starving cancer cells through dietary manipulation: methods and clinical implications