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Previous studies have combined short-access models (2 h) and long-access models (more than 6 h) 86,87,88 or adjusted the FR schedule 89 to better simulate the drug intake or seeking behaviors observed in humans

The decreased plasma free fatty acid concentrations with carnitine supplementation may be due to more efficient fatty acid oxidation and/or increased urinary excretion of fatty acids as acylcarnitines

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Median and 5th-to-95th percentile ranges are shown for both interaliquot and interpatient variability (adapted from Plauzolles et al, 2022)

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