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We also observed increased siRNA loading capacity with lower NP to siRNA w/w ratio compared to previous studies (Darvishi et al., 2013)

Enhanced expression of egr-1 was combined with a multitude of pathologies (i.e., atherosclerosis [159], stenosed calcific valvular disease [161], cardiac hypertrophy [162,163], cerebral ischemia [164], and tumor progression [158,165,166,167])

The peptide samples were separated with an ACN gradient (690%) run for 210 min by mixing solvent A (2% ACN and 0.1% v/v formic acid) and solvent B (100% acetonitrile and 0.1% v/v formic acid) in varying proportions in all samples

Once reconstituted, peptides begin to experience hydrolytic and enzymatic degradation, even when refrigerated

doi: 10.4103/1673-5374.366493