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Advanced molecular studies reveal that FOXO4-DRI promotes p53 nuclear exclusion and subsequent mitochondrial targeting, where p53 interacts with BCL-2 family proteins to promote mitochondrial outer membrane permeabilization and cytochrome c release

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CrossRef Trend Analysis and Prediction of Hepatobiliary Pancreatic Cancer Incidence and Mortality in Korea Hyeong Min Park, Young-Joo Won, Mee Joo Kang, Sang-Jae Park, Sun-Whe Kim, Kyu-Won Jung, Sung-Sik Han Journal of Korean Medical Science.2022;[Epub] CrossRef Conditional Survival of Patients Who Underwent Curative Resection for Esophageal Squamous Cell Carcinoma Dong Wook Shin, Hong Kwan Kim, Jongho Cho, Genehee Lee, Juhee Cho, Jung Eun Yoo, Sumin Shin, Yong Soo Choi, Young Mog Shim, Jae Ill Zo Annals of Surgery.2022

Mutations in any of the genes encoding for proteins regulating pyruvate metabolism may lead to disease