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Known for dose-dependent responses in controlled settings

doi: 10.1016/j.metabol.2014.11.009

Behavioral Pharmacology

Moreover, despite the increasing awareness of the ubiquity of microplastics (MPs) in our environments, little is known so far about their risk of developmental toxicity

The finding that itaconate can activate the Nrf2 signaling pathways by alkylation of Keap1, thereby initiating the transcription of pro-inflammatory and anti-oxidant genes, has made itaconate a promising candidate for therapeutic applications in a variety of diseases and tissue types [4]
