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Thus, this increase in S-5-HT from before to after L-carnitine was about 8-fold in CFS and 6-fold in hypothyroidism

Si te interesa otro caso de forma qumica con efectos muy distintos, puedes leer qu le pasa a los principios activos de la maca cuando aplicas calor en el proceso de gelatinizacin.

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The reason is that only one nucleotide substitution is needed relative to the subtype 1a sequence to generate this variant, whereas two substitutions are needed relative to the 1b sequence (codon usage bias)
