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About this article Cite this article Deepika, Shekhawat, J., Madhu et al

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Thus the use of human iPSC-derived brain organoids can not only help us better understand the mechanisms underlying the regulation of adult hippocampal neurogenesis, but also provides a new tool to study differences in donor phenotypes based on the transcriptional responses of genes and the time and context-specific epigenomic profiles at various developmental stages