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On the contrary, TP53 mutations are more common in SCC cells, suggesting that AC NSCLC cell lines mainly metabolize glutamine, whereas SCC cell lines mainly metabolize glucose (14)

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Notably, DBDS can be incorporated into composite nanoarchitectures (DBDS-NAs) to improve drug delivery, further potentiating its role as a ferroptosis-inducing agent in the treatment of PDAC [25]