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192 Wnt/-catenin pathway in cancer In 1982, the first WNT gene was identified and cloned as an oncogene in mouse breast cancer

In situations where other treatments might not be sufficient, it has been investigated for its potential to help with ulcers, leaky gut, and even some symptoms of IBD

This trial is detailed in the comprehensive review by Pickart et al
Important point #3
For example, animal studies show mast cells in the colon release prostaglandin E2, causing pain and hypersensitivity in IBS (irritable bowel syndrome)
