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This can be through (a) the direct alkylation of DNA through the activation of drugs like mitomycin C and RH1 into alkylating groups, (b) the inactivation of heat shock proteins by geldanamycin hydroquinones generated by the enzyme, and (c) in contrast to the known metabolic process of NQO1, certain naturally occurring or synthetic quinone compounds produce labile forms of hydroquinone [39,40,41,42]

M.MccaughanG.WangB.WangX.et al (2024)

(2025) 12:e2413759

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The ratio of diameter change compared with the original size was 0.69 0.02, 0.72 0.02, 0.73 0.04, and 1.35 0.03 in control, 1.0 g/ml BPC 157, 100 g/ml BPC 157 and 200 M SNP, respectively (Fig