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When comparing their fibroblasts, it was found that Nip3-like protein X, which may mediate a Parkin/PINK1-independent pathway in eliminating damaged mitochondria, was highly upregulated in the asymptomatic carrier

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J Appl Biochem 5:4352 Hibi T, Nii H, Nakatsu T, Kimura A, Kato H, Hiratake J, Oda J (2004) Crystal structure of gamma-glutamylcysteine synthetase: insights into the mechanism of catalysis by a key enzyme for glutathione homeostasis