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Accordingly, we next employed preclinical models of kidney injury to gain mechanistic insights into the potential interplay between TMAO and kidney function and the putative molecular nature of the 2nd hit

CPT II : carnitina-palmitoil-transferasi II , presente sulla parte interna della membrana mitocondriale interna, catalizza la reazione inversa alla CPT I, riformando acil-CoA per carnitina-acilcarnitina translocasibeta ossidazione

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Furthermore, upregulation of the PI3K/AKT/mTOR pathway is involved in the neuroinflammation and neuronal autophagy of ASD [29, 60]

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