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Furthermore, mice colonic transcriptome analysis revealed that CNCM I-3690 enhanced the expression of genes related to healthy gut permeability: motility and absorption, cell proliferation

Some common sources of differences in 1,4-dioxane toxicity values include selection of the critical effect, how the point of departure (POD) was calculated (i.e., use of administered dose or use of benchmark dose [BMD] modeling), and the selection of uncertainty factors

Grouping: Control group (physiological saline intra-articular injection), AOD 9604 group (0.25mg/joint), hyaluronic acid (HA) group (0.5mg/joint), AOD 9604+HA combination group

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