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Description
This extrapolation involves two critical decisions: (1) selecting a point of departure (POD), which corresponds to the lowest dose associated with observable adverse effects within the range of data from a study, and (2) selecting the mathematical model used to extrapolate risk from typical human exposures that are well below the POD

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There is no clinical evidence linking GHK-Cu to any serious safety issues

The timeline is too short

doi: 10.1038/ncb1117
