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Evidence for sustained elevation of IL-6 in the CNS as a key contributor of depressive-like phenotypes

Based on standard FDA review timelines (12 months for priority review), approval is expected in 20262027

These include: Older adults, as they absorb B12 less easily Vegetarians and vegans, because B12 is mostly in animal products People with stomach problems like celiac disease or Crohns disease Those who have had gastric bypass surgery Knowing these risk factors helps find who might need to check their B12 levels

USA 118 , e2021096118 (2021)

The GLP-1 receptor activation in both drugs improves insulin secretion and glycemic control