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doi: 10.3390/biom13050820 98 ParkEChungSW

experimentally validated ICAM-1 as a dual-function target, demonstrating its utility as both a therapeutic vulnerability and a potential prognostic biomarker [38]

Likewise, as occurring with oral supplementation, the bioavailability of polyphenols present in foods is in general low, and in vitro, studies observed clear differences in the mechanisms of polyphenols when used in their pure form and at high concentrations versus when ingested through foods rich in these compounds [600]

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