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DAM release superoxide radicals (i.e., ROS), nitric oxides, and pro-inflammatory cytokines and factors (IL-1, TNF-, C1q), which induce neurotoxic C3 + reactive astrocytes (Liddelow et al., 2017)

doi: 10.1016/j.cgh.2016.12.039

Techniques such as enzyme assays and mass spectrometry are used to measure NADPH concentrations and assess how shifts in NADPH production impact cellular functions

This leaves HIV patients at greater risk to opportunistic infections, such as Mtb , the leading cause of death in HIV patients worldwide [13]

J Neuroimmune Pharmacol 9:424437 Balijepalli S, Kenchappa RS, Boyd MR, Ravindranath V (2001) Protein thiol oxidation by haloperidol results in inhibition of mitochondrial complex I in brain regions: comparison with atypical antipsychotics