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N Engl J Med 380(22):2095-2103, 2019

Participants 16 Years of Age and Older At the time of the analysis of Study 2 for the EUA, 37,586 [18,801 Pfizer-BioNTech COVID-19 Vaccine (30 mcg modRNA) and 18,785 placebo] participants 16 years of age or older had been followed for a median of 2 months after the second dose

The complexity of certain treatments, such as those requiring intravitreal injections or continuous monitoring, may discourage patients from consistently following their prescribed regimens (106)

These advantages not only increase the effectiveness of the treatment, but also reduce the risk of adverse effects, thus contributing to a safer and more effective therapy for patients with chronic and acute respiratory conditions

RNA sequencing analysis further indicated that only the dysregulated genes associated with complex III are linked to ROS pathways, suggesting a ROS generation pathway involving complex III that bypasses complex I [68]