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Description
CRISPR-Cas9 targeting of PI3K/AKT/mTOR growth pathway inhibitors PTEN 19 and STK11 induced resistance, while loss of pathway activators GAB2 and LAMTOR5 increased sensitivity (Fig

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NLRP3 senses a wide array of endogenous and exogenous danger signals, including microbial products, environmental toxins, and host-derived DAMPs, making it a central player in inflammatory responses