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Thus, EBV-infected cells require zinc for increased overexpression of MTs and for transactivation of EBNA-1, thereby increasing their intracellular levels by increasing the expression of zinc transporters and favoring zinc release from metallothioneins via the action of increased ROS, ultimately aiding in the activation, proliferation, and immortalization of transformed B cells [330, 332,333,334]

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Briand L, Marcion G, Kriznik A, Heydel J-M, Artur Y, Garrido C, Seigneuric R, Neiers F

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Nanobiotechnology 20 (1), 310

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Detoxification: In the liver, GSH is utilized by the enzyme Glutathione S-Transferase (GST) to bind, or conjugate , toxins (a key step in Phase II detoxification)

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Ferroptosis, a non-apoptotic form of programmed cell death (PCD), is closely related to NAFLD and HCC, and the mechanisms of action involved are more complex

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