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In this study, aiming to understand the essential role of NDRG1 in ECs in response to the potent angiogenic factor VEGF-A, we assessed the effect on angiogenesis of NDRG1 deficiency in ECs in response to VEGF-A and another potent angiogenic factor fibroblast growth factor (FGF)-2

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70,82 On one hand, COX17 binds to and delivers Cu to the synthesis of cytochrome c oxidase 1 (SCO1) or SCO2, which then transfers the Cu to the CuA site in the core subunit of COX2

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