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Metabolic effects of aspartame in adulthood: A systematic review and meta-analysis of randomized clinical trials

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op den Camp RG, Przybyla D, Ochsenbein C, Laloi C, Kim C, Danon A, et al

Furthermore, there was a notable upregulation in the protein expression of Cyt c, caspase-9 and caspase-3, along with a considerable increase in apoptotic cell count and extensive mitochondrial vacuolation, as evidenced by transmission electron microscopy

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