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Administration of an appetite stimulant (eg, mirtazapine, cyproheptadine) rarely induces caloric intake sufficient to reverse hepatic lipidosis and should be used only as a salvage intervention if proper nutritional support has been declined

140,141 TBK1 mediates the activation of nuclear factor-B (NF-B) and interferon (IFN) regulatory factor 3 (IRF3)
10.1038/s41392-021-00679-0 Signal Transduct Target Ther

Then, the solution was given to the mice at the dosage of 10 mg/kg
Santonen T, Mahiout S, Alvito P et al (2023) How to use human biomonitoring in chemical risk assessment: methodological aspects, recommendations, and lessons learned from HBM4EU