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The authors also identified the idea that cytosine-phosphate-guanine motif (CpG islands) which are found mainly in regulatory regions are the target of most DNA methylation and gene expression

NADPH oxidase 4 (NOX4) contributes to DED progression by modulating IL-1, NLRP3, and MUC5AC expression

[DOI] [PubMed] [Google Scholar] 475

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