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Research spanning 2-3 years of intermittent cycling shows no significant long-term complications in healthy adults

doi: 10.1038/s41551-019-0359-6 59 RaffinCVoLTBluestoneJA
Severe neuropathy in the legs and feet can cause chronic pain, numbness, and mobility issues , affecting daily life

doi: 10.1097/01.prs.0000225430.42531.c2

Neurovascular unit dysfunction and bloodbrain barrier hyperpermeability contribute to schizophrenia neurobiology: a theoretical integration of clinical and experimental evidence
