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Discontinuation may be warranted if allergic reactions occur, if side effects persist despite slower dosing, or if baseline conditions (acute kidney injury, active infection) change

doi: 10.1007/s11695-014-1225-y

Seek medical advice for persistent bowel changes, blood in stools, unexplained weight loss, or severe abdominal pain

Research examining supplement quality found that 30% of tested products contained incorrect amino acid sequences and 65% exceeded safe endotoxin thresholds