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During corticosteroid therapy may occur psychological disorders such as: euphoria, insomnia, mood swings, depression or personality disorders and even severe depression or psychosis

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Functional B12 deficiency correlates with functional B2 deficiency .Functional vitamin B2 deficiency as determined by levels of glutaric acid in urine, correlated with both the classical marker of AdenosylB12 deficiency, as MMA gradually increased as glutaric acid levels increased, and with neurological markers of Methyl B12 deficiency