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Fungal chitin dampens inflammation through IL-10 induction mediated by NOD2 and TLR9 activation
The fact that it can't be removed isn't a limitation
doi: 10.1093/af/vfac078, 3
CHAC2 itself is regulated both transcriptionally and post-translationally, with its degradation mediated by the ubiquitin-proteasome pathway ( In lung cancer, however, the CHAC2-mediated increase in ROS triggers the MAPK pathway
Heme-stress activated NRF2 skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages in hemolytic anemia
