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ADCs combine the high specificity of monoclonal antibodies in recognizing tumor cells with the potent killing power of small-molecule cytotoxic drugs, introducing the concept of "targeted delivery" into chemotherapy drug delivery

FDA Status and Ongoing Research Sermorelin had FDA-approved injection products in the 1990s for pediatric growth hormone deficiency and for evaluating GH secretion, but the manufacturer discontinued them and FDA withdrew the NDAs in 2009

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doi:10.1016/s0004-9514(06)70026-5 Teixeira LJ, Valbuza JS, Prado GF

Recently, research has focused on whether disturbance in the balance of commensal microbial species may be carcinogenic and could provide a mechanistic link between dietary and lifestyle aetiological risk factors in CRC development (17)