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In adults and older children, the total volume used should also stay within safe limits animal studies suggest up to about 30 mL (the full vial) can be given to an adult without benzyl-alcohol toxicity, but one should still use only the amount needed and discard the rest if sterility is lost

Consequently, disrupting this vicious cycle represents a compelling and conceptually unified frontier for cancer therapy, a strategy that will be examined in the following sections ( Figure 2 )

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