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Importantly, when researchers blocked TGF- signaling, the pro-bone benefits of MOTS-c were diminished, confirming that the TGF-/Smad pathway is crucial to MOTS-cs action in bone
Ferroptosis is a form of cell death characterized by a lack of control of membrane lipid peroxidation and recent studies have suggested that chondrocyte ferroptosis contributes to OA progression
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