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Targeting insulin-like growth factor binding protein-3 signaling in triple-negative breast cancer

Previous research findings have shown that the sublingual form of glutathione has superior bioavailability compared to oral administration [15, 16] Using a sublingual formulation of GSH as a supplement might potentially serve as a beneficial approach to enhancing the inherent antioxidant defense mechanisms necessary for mitigating various acute and chronic illnesses

Glutathione conjugation catalyzed by GST (glutathione-S-transferase) of AFBO is a major route of detoxification, forming an inert metabolite that is not able to react with the DNA (Rushing and Selim, 2019)

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Two pairs of oxidation-reduction peaks were observed in the cyclic voltammetry curve of TMB in the acetate buffer (pH=4.0, Fig