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Neighborhood deprivation and clinical outcomes among head and neck cancer patients

notably described that the substitution of the first 290 residues of MRP1 by the corresponding residues of MRP2, like in chimera M1, leads to a complete absence of addressing to the plasma membrane with a retention in the endoplasmic reticulum 19

Hladky SB, Barrand MA

Cyclophosphamide, doxorubicin, and cisplatin combination chemotherapy for advanced carcinomas of salivary gland origin showed encouraging results (Dreyfuss, Clark et al., 1987)

However, the report notes that Ashcroft scores dropped to 1.671.01 when mice were administered both bleomycin and M10, suggesting the anti-fibrotic potential of this peptide