cagrilintide and semaglutide 2.4mg.... Efficacy safety of once-weekly cagrilintide–semaglutide (CagriSema) in adults with type 2 diabetes inadequately controlled on diet and exercise (REIMAGINE 1): a randomised, double-blind, placebo-controlled, phase 3a study Safety, tolerability, pharmacokinetics, and pharmacodynamics

Lets see what existing studiesalbeit mostly in animalstell us

JAM-A-deficient mice have increased barrier permeability with elevated bacterial translocation

(11) Studies have examined the compounds bioavailability following various routes of administration and its tissue distribution patterns

Although some compounding pharmacies meet high manufacturing standards and submit to third-party testing, variability in purity, potency, and sterility persists, especially among unregulated, direct-to-consumer online sources

Some literature indicated that repeated and long term IM injections in the same location can cause scar tissue