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It functions as an electron carrier within the inner mitochondrial membrane, facilitating the transfer of electrons from complexes (I, II) to complex III, thus promoting the synthesis of adenosine triphosphate (ATP)

Selective HDAC6 inhibitors, such as TubA, ACY-1215 (ricolinostat), Tubacin and ACY-738, have already shown pre-clinical efficacy across neurodegenerative, cardiovascular, metabolic and oncological models by reducing oxidative damage, restoring proteostasis and improving cell survival (162)

Cells 2021;10(6):1547

Research hotspots in the application of hormesis include keywords related to inflammation and neurotic (light blue), herbicide and insecticide, and sublethal effect (dark blue)

However, as peptides break down, they can lose their structure and charge, leading to fragmentation and eventual loss of structural integrity