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Along with other components like collagen and fibronectin, GAGs play a role in the pathophysiological processes at different stages of the diseases progression (Richter et al., 2010) (Treutlein et al., 2012)

The controversial expression pattern of GPx1 in breast cancers requires further investigation to determine its molecular functions

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Notably, all patients had previously been treated with pentosan polysulfate, which is currently the only FDA approved treatment for interstitial cystitis, and had not responded

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