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Many pharmaceutical companies have tried to develop drugs that target Mcl-1, but this has been difficult because the interaction between Mcl-1 and its target protein occurs in a long stretch of 20 to 25 amino acids, which is difficult to block with the small molecules typically used as drugs

"I think there's a link" between vitamin B12 and acne, said Huiying Li, a co-author of the new study and an assistant professor of pharmacology at UCLA's David Geffen School of Medicine

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