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After remov- ing duplicates and completing the screening processes, we included 36 articles in this systematic review [1,2,47,15 20,22,23,25,33,35,36,39,40,41,4453,6062,66,67], with 21 reporting on the mechanism of action [1,2,5,6,16 20,23,35,40,41,47,50,52,53,6062,66], 15 reporting muscu- loskeletal outcomes [2,46,19,22,22,25,33,36,39,46,48,49], 3 analyzing metabolism [7,15,51], and 4 assessing safety profile and adverse effects associated with BPC-157 [15,45,45,67] (Fig

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503,504 Osteoporosis Hypogonadism is a well-established cause of osteoporosis

On the other hand, sulbutiamine is a cofactor of an enzyme that is crucial for the production of GABA the main inhibitory neurotransmitter capable of lowering stress levels

An elevated vitamin B12 level often reflects increased intake (oral supplementation, recent intramuscular injection) or high dietary consumption, especially from fortified foods or animal products