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Description
In 1934, George Hoyt Whipple (University of Rochester), George Richards Minot (Harvard University), and William Parry Murphy (Harvard University) were awarded the Nobel Prize in Physiology/Medicine for their discoveries concerning liver therapy in cases of anemia (for proving that it is possible to cure a serious blood disease called pernicious anemia by means of liver extracts) [32]

Key Biomarkers: Homocysteine Methylmalonic acid Tracking these biomarkers helps doctors diagnose and treat B12 deficiency in thalassemia patients better

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Additional research is exploring its role in angiogenic signaling, cellular turnover, and oxidative stress response pathways
Overall, T1D is fundamentally a disease of immune tolerance failure, evidenced by the retention and subsequent activation of autoreactive CD8+ T cells that infiltrate the pancreas
